Early Stage Malignant Lymphoma of the Stomach, Report of a Case Masahiro Nagano 1 , Fukuji Mochizuki 1 , Shyoichiro Itoh 1 , Taku Ikeda 1 , Tokiaki Toyohara 1 1Department of Gastroenterology, Sendai City Medical Center pp.317-322
Published Date 1988/3/25
DOI https://doi.org/10.11477/mf.1403107966
  • Abstract
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 A 46 year-old man was referred to our hospital for surgical treatment of malignant lymphoma of the stomach. This diagnosis had been made by the referring physician based on the biopsy findings of ulcer margin (Fig. 1,2 a,2 b) . During the hospitalization radiological examinations were performed as well as endoscopic examinations twice each (Fig. 3~6).

 In the course of observation, an irregular ulceration on the anterior wall of the angulus has markedly diminished in size (Fig. 6), while an ear-lobe shaped, elevated lesion had become clearly detected in 18 days.

 The diagnosis of malignant lymphoma of the stomach was made based on these biopsy findings and clinical course.

 Gastric resection was performed. A shallow depression with converging folds (Fig. 7) and the ear-lobe shaped, elevated lesion on its greater curvature side (Fig. 8 a) were observed macroscopically in the resected specimen.

 Histologically, infiltration of malignant lymphoma was limited to the submucosa (Fig. 8 b, c) and regional lymph nodes were free from invasion.

 Although there have been several reports on the maked changed in appearances of early malignant lymphoma of the stomach in a relatively short period of time, our present case, seemingly the most typical one, highly suggests the existence of such a “malignant cycle” in early malignant lymphoma as that seen in early gastric cancer.

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