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Histopathological Studies of Anal Malignancies with Special Reference to Basaloid Carcinoma I. Nakada 1 , I. Kino 2 , Y. Kato 3 , D. Hashimoto 1 , S. Hosaka 1 1Department of Pathology, University of Tokyo School of Medicine 2Department of Pathology, Hamamatsu University School of Medicine 3Department of Pathology, Cancer Institute pp.1141-1147
Published Date 1978/8/25
DOI https://doi.org/10.11477/mf.1403107412
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 The purpose of this paper is to describe histopathology of 18 cases of malignant tumors of the anal region, excluding adenocarcinoma of the rectal type, seen at Tokyo University Hospital during the years 1955~76.

 The following histopathological types were classified: adenocarcinoma probably arising from the anal glands (3 cases), adenocarcinoma associated with anal fistula (1), squamous cell carcinoma (6), basaloid carcinoma (5), adenoacanthoma (1), malignant melanoma (1), and basal cell carcinoma of the perianal skin (1).

 Five cases of basaloid carcinoma of the anal canal in particular are extensively discussed. Although various diagnostic terms, such as transitional cloacogenic, basosquamous, undifferentiated and others, have been used by different investigators to describe the similar lesions, we prefer the term, basaloid carcinoma, to others because of its purely descriptive nature and expression of histological characteristics. Basaloid carcinomas resemble basal cell carcinoma of the skin, especially in that palisading of the nuclei at the periphery of the tumor cell nests is present.

 While basaloid carcinoma is predominantly basaloid, sharply difined pearls of keratin are occasionally demonstrated. In our experience there are at times small foci of basaloid structure in other squamous cell carcinomas of the anal canal as well as esophagus.

 We consider that basaloid carcinoma of the anal canal is not a strictly independent type, but a variation of squamous cell carcinoma.


Copyright © 1978, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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