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Japanese

AGML: Its Causes and Clinical Aspects Kazumichi Harada 1 1The Third Department of Internal Medicine, Asahikawa Medical College pp.637-644
Published Date 1989/6/25
DOI https://doi.org/10.11477/mf.1403106475
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 Major causes of AGML (acute gastric mucosal lesion) were classified as follows; (1) emotional stress, (2) drug ingestion, (3) alcoholic consumption and diet, and (4) vascular changes. Among these, emotional stress was the most leading cause with multiple hemorrhagic erosions and ulcerative changes. In patients with drug ingestion-associated AGML, non-steroidal antiinflammatory drugs were most frequently administered, causing AGML in a week after administration. Relationship between presence of symptoms and severity of endoscopic findings did not always exist. Most of the patients with drug-associated AGML were 65-years of age or older, suggesting the relationship between AGML in the elderly and decreased defence mechanisms of gastric mucosa. It was noted that AGML associated with dietary consumption of garlic and hot spices has been increasingly noted. Acute giant ulcer in the body of the stomach in the elderly was thought to be associated with vascular changes similar to those seen in acute occlusion of mesenteric artery. Prognosis of patients with AGML due to any cause was relatively good and the author experienced no case pursuing a chronic course. Follow-up study of AGML by endoscopy remains to be done.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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