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The Posibility of Making a Diagnosis of Crohn's Disease by Upper Gastrointestinal Examinations Nobuo Hiwatashi 1 , Hiromitsu Watanabe 1 , Satoshi Moriyama 1 , Akio Shirane 2 1The Third Department of Internal Medicine, Tohoku University School of Medicine 2Shirane Icho Clinic Keyword: Crohn病 , 上部消化管病変 , 非乾酩性肉芽腫 , びらん pp.1369-1376
Published Date 1994/12/25
DOI https://doi.org/10.11477/mf.1403106015
  • Abstract
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 We investigated whether a diagnosis of Crohn's disease can be made by upper gastrointestinal examinations before it has became clear by other methods that a patient is suffering from Crohn's disease. The subjects consisted of 38 patients, who had been neither operated on nor examined by x-ray and/or endoscope. There was no patient diagnosed as having Crohn's disease by upper gastrointestinal examinations including biopsies through an endoscope. However, small ulcers and erosions arranged longitudinally and multiple erosions in the duodenum were considered to be characteristic findings indicating gastroduodenal lesions of Crohn's disease. Epitheloid cell granulomas were detected in three cases among ten biopsied cases.

 In future, when we try to diagnose unusual cases without typical clinical symptoms or data, and cases consisting solely of aphthoid ulcers throughout the alimentary tract, detection of upper gastrointestinal lesions and/or the presence of epitheloid cell granulomas in biopsy specimens, may come to be regarded as conclusive evidence of Crohn's disease.


Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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