Stomach and Intestine(Tokyo) Volume 46, Issue 12 (November 2011)

Pathologic Analysis of the Adenocarcinoma of the Lower Esophagus and Esophagogastric Junction, including Barrett's Adenocarcinoma and Non-Barrett's Adenocarcinoma Hiroshi Kawachi 1 , Naoki Akazawa 1 , Kenro Kawada 2 , Tomoyoshi Suzuki 2 , Mariko Negi 1 , Eisaku Ito 1 , Tatsuyuki Kawano 2 1Department of Human Pathology, Tokyo Medical and Dental University, Tokyo 2Department of Esophageal and General Surgery, Tokyo Medical and Dental Univerisity, Tokyo Keyword: Barrett食道 , 食道胃接合部 , 腺癌 , 胃食道逆流症 , 噴門部 pp.1762-1776
Published Date 2011/11/25
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 Totally 26 cases of adenocarcinoma of the lower esophagus and EGJ(esophagogastric junction), limited to the mucosa or submucosa, were examined. There were no significant differences in pathologic characteristics among three groups of esophageal adenocarcinoma, adenocarcinoma of the esophagogastric junction, and adenocarcinoma of the proximal stomach. However, the existences of a poorly differentiated component, 0-IIb component, and atypical glands with indefinite for neoplasia were relatively frequent in the lesions with greater length in the Barrett's esophagus. Although adenocarcinomas of the lower esophagus and esophagogastric junction have been found under the common condition of gastroesophageal reflux disease, they may be divided into two groups such as adenocarcinoma with and without preceding Barrett's mucosa. For the latter group, Barrett's esophagus may be a paracancerous condition rather than a precancerous lesion.

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46巻12号 (2011年11月)
電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院