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Histologic Examination of Barrett's Esophagus Gen Watanabe 1 , Yoichi Ajioka 1 1Division of Molecular and Diagnostic Pathology, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan Keyword: Barrett食道 , 食道胃接合部 , 食道腺 , 二重粘膜筋板 , 噴門腺粘膜 pp.1750-1761
Published Date 2011/11/25
DOI https://doi.org/10.11477/mf.1403102402
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 Barrett's esophagus is an abnormal condition in which the squamocolumnar junction(SCJ)is located proximal to the esophagogastric junction(EGJ), whereas EGJ and SCJ is the same level in normal conditions. The tissue between EGJ and SCJ is lined by columnar epithelium in the Barrett's esophagus. It is easy to identify the SCJ histologically, but it is difficult to histologically determine the line of EGJ defined as the anatomical muscular boundary or the lower end of palisading vessels. Meanwhile we can identify the region of EGJ in reference to histologically reliable markers(esophageal glands and their ducts, esophageal islands, and double muscularis mucosae)indicating the esophageal origin and helpful markers(multilayered epithelium, cardiac glands, and fundic glands). We should know the limitations of histologic examination and take account of clinical information especially when diagnosing junctional cancers.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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