Stomach and Intestine(Tokyo) Volume 46, Issue 4 (April 2011)

Endoscopic Diagnosis of Colorectal Serrated Lesions Tomoaki Kimura 1 , Hiro-o Yamano 1 , Tamotsu Sugai 2 , Kenjiro Yoshikawa 1 , Taku Harada 1 , Ryo Takagi 1 , Taro Abe 1 , Ryo Suzuki 1 , Koujiro Tokutake 1 , Masayo Okunomiya 1 , Michiko Nakaoka 1 , Kentaro Satou 1 , Yasushi Imai 1 , Eiichiro Yamamoto 3 , Seiko Kamimae 3 , Minoru Toyota 3 1Department of Gastroenterology, Akita Red Cross Hospital, Akita, Japan 2Division of Diagnostic Molecular Pathology, Department of Pathology, Iwate Medical University, Morioka, Japan 3Department of Biochemistry, Sapporo Medical University, Sapporo, Japan Keyword: 大腸鋸歯状病変群 , pit pattern診断 , SSA/P , TSA pp.418-426
Published Date 2011/4/25
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 So-called“serrated lesions”included hyperplasic lesion, sessile serrated adenoma/polyp, traditional serrated adenoma, adenoma with serration, etc. Recently, a kind of“serrated lesion”has been reported to be the precursors of colorectal cancer with microsatellite instability although little is known about endoscopic findings of such lesions. On the other hand, this type of“serrated lesion”is currently recognized even though endoscopic diagnosis of“serrated lesions”has not yet been established. In the present study, we recognized several surface micro-structures of “serrated lesions”by using magnifying colonoscopy, and compared them with pathological diagnosis. As a result, we found that endoscopic findings were correlated with pathological diagnosis during the tumorigenesis of colorectal cancer. Further study will be needed to establish endoscopic diagnosis for“serrated lesions”by magnifying colonoscopy.

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46巻4号 (2011年4月)
電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院