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要旨 目的:表面隆起型胃腫瘍の異型度別にみたX線・組織所見の特徴を明らかにする.対象と方法:内視鏡的一括切除を行った胃粘膜内病変のうち,表面隆起型形態を呈した91病変(腺腫 21,低異度分化型癌 31,高異型度分化型癌 39)を対象とし解析を行った.結果:(1)高異型度癌と低異型度癌の差異に関して,高異型度癌は低異型度癌に比べ杯細胞化生が少なく,劣勢分化度が中~低分化,全層主体の発育形式が多く,長径が有意に大きかったが,X線所見では差が認められなかった.(2)低異型度癌と腺腫の差異に関しては,各因子に差がなく類似性が高かったが,低異型度癌では表層の櫛状突起とX線的な微細顆粒模様ありの割合が有意に多かった.(3)微細顆粒模様の組織学的成因は,表層の櫛状突起と長径が独立した因子であった.(4)微細顆粒模様による腺腫と低異型度癌の鑑別診断能は,感度83.6%,特異度57.1%,正診率73.1%であった.結論:表面隆起型低異型度癌は,組織学的に高異型度癌よりも腺腫に類似性が高いが,表層の櫛状突起とX線的な微細顆粒模様の有無が腺腫との鑑別に有用である.
Aims : We tried to clarify the radiographic and histological characteristics of superfietial protruded type gastric neoplasia . Material : 91 lesions of gastric cancer and adenoma clearly verified by histology. Method : We analyzed the clinico-pathological factors related to the degrees of histological atypia(adenoma, low-grade and high-grade of differentiated type carcinoma). Results : Histological findings ; a meaningful difference between low-grade carcinoma and adenoma was recognized by a comb-shaped projection of the mucosal surface. Radiographic findings ; A meaningful difference was recognized by a fine granular pattern. Conclusions : In radiographic diagnosis related to the degrees of histological atypia, the presence of a fine granular pattern with a comb-shaped projection of the mucosal surface is the most important factor.
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