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Endoscopic and Histopathological Features of Low Grade Gastric Differentiated Adenocarcinoma Kenichiro Imai 1 , Hiroyuki Ono 1 , Naomi Kakushima 1 , Kohei Takizawa 1 , Masaki Tanaka 1 , Yongze Huang 1 , Hiroaki Sawai 1 , Norifumi Nishide 1 , Hiroyuki Matsubayashi 1 , Yuichiro Yamaguchi 1 , Tadakazu Shimoda 2 , Takashi Nakajima 3 1Department of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan 2Center for Cancer Control and Information Services, National Cancer Center, Tokyo 3Department of Pathology, Shizuoka Cancer Center, Shizuoka, Japan Keyword: 低異型度癌 , 範囲診断 , 内視鏡診断 , 胃型 , ESD pp.1131-1144
Published Date 2010/6/25
DOI https://doi.org/10.11477/mf.1403101969
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 To clarify endoscopic and histopathological features of low grade gastric differentiated adenocarcinoma, 313 early gastric cancers(EGC)were divided into 116 low grade cancers(LGC)and 197 high grade cancers(HGC)according to their histological features. Firstly, we investigated the endoscopic features of LGC in comparison with HGC. Secondly, we evaluated the predictive factor of endoscopically obscure margin with chromoendoscopy. Significant endoscopic and pathologic features of LGC were,“isochromatic and pale",“less than 20mm in diameter",“without concomitant ulcer",“mucosal lobulated pattern preserved" and “obscure margin in chromoendoscopy". In pre-assessment of ESD for LGC, the lateral margin of the lesion could be demarcated clearly in three quarters of the circumferences, however there was usually a small portion with obscure margin. We conclude that a full examination into that partial obscure margin is important for achieving a curative resection of LGC by endoscopic submucosal dissection.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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