雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

Stomach and Intestine(Tokyo) Volume 44, Issue 3 （March 2009）

胃と腸 44巻3号（2009年3月発行）

Japanese English

早期胃癌研究会症例

1型を呈し腺癌と扁平上皮癌の併存が確認された胃内分泌細胞癌の1例 Type 1 Carcinoma, which Includes Endocrine Cell Carcinoma with Adenocarcinoma and Squamous Cell Carcinoma in the Stomach, Report of a Case 勝浦清竹 ¹ , 大原正志 ² , 加藤久人 ³ , 酒井裕司 ⁴ , 細川勇 ⁵ , 近藤福雄 ⁶ Kiyotake Katsuura ¹ , Tadashi Ohara ² , Hisahito Katou ³ , Yuji Sakai ⁴ , Isamu Hosokawa ⁵ , Fukuo Kondo ⁶ ¹社会保険船橋中央病院内科 ²国際医療福祉大学病院消化器内科 ³社会保険中央総合病院 ⁴千葉大学医学部腫瘍内科 ⁵社会保険船橋中央病院外科 ⁶帝京大医学医学部病理学 ¹Department of Internal Medicine, Funabashi Central Hospital, Funadashi, Japan ²Department of Gastroenterology, International University of Health and Welfare Hospital, Nasushiobara, Japan ³Department of Health Center, Social Insurance Central General Hospital, Tokyo ⁴Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan ⁵Department of Surgery, Funabashi Central Hospital, Funabashi, Japan ⁶Department of Pathology, Teikyo University School of Medicine, Tokyo キーワード：内分泌細胞癌 , 1型 , 胃 Keyword: 内分泌細胞癌 , 1型 , 胃 pp.433-439

発行日 2009年3月25日 Published Date 2009/3/25

DOI https://doi.org/10.11477/mf.1403101614

PDF(861KB)

有料閲覧

Abstract 文献概要
1ページ目 Look Inside
参考文献 Reference

要旨　患者は，70歳，男性．2001年より，当院呼吸器内科にて慢性膿胸で通院中，上腹部不快感を訴え，胃内視鏡検査を施行した．胃体下部小彎に約3cm大の1型癌を認めた．生検で内分泌細胞癌が診断され，外科にて胃亜全摘術を施行した．腫瘍径は25×15mmであった．本例は，1型の形態を呈した胃内分泌細胞癌であり，なおかつ病理組織学的には内分泌細胞癌に中分化型管状腺癌と扁平上皮癌の併存が認められた稀有な症例であった．

　A 70-year-old man was admitted to our hospital with epigastralgia as his chief complaint. Gastroendoscopy showed a type 1 lesion on the lesser curvature of the lower corpus of the stomach. The histological diagnosis of the biopsy specimen of the lesion was endocrine cell carcinoma. No metastatic lesion in any organ was detected through examination of abdominal CT and PET. Subtotal gastrectomy and D2 lymph node dissection were performed. The resected specimen from the lesser curvature of the lower corpus of the stomach showed a type 1 carcinoma. The size was 25×15mm. The histopathological examination showed the carcinoma consisted of endocrine cell carcinoma, adenocarcinoma and squamous cell carcinoma. The endocrine cell carcinoma mostly occupied the type 1 carcinoma. The adenocarcinoma existed around the type 1 carcinoma. Squamous cell carcinoma was seen slightly in the endocrine cell carcinoma. The endocrine cell carcinoma cells were stained with chromogranin A and adenocarcinoma cells were stained with CEA, and so the diagnosis was endocrine cell carcinoma with adenocarcinoma and squamous carcinoma. We report this, because type 1 carcinoma involving endocrine cell carcinoma with adenocarcinoma and squamous cell carcinoma, is very rare in Japan.