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Prognosis of Esophageal Squamous Cell Carcinoma Treated by Endoscopic Submucosal Dissection Tsuneo Oyama 1 , Yoko Kitamura 1 , Akihisa Tomori 1 , Kin-ichi Hotta 1 , Akiko Takahashi 1 , Yoshinori Miyata. 1 1Department of Gastroenterology, Saku Central Hospital, Saku, Japan Keyword: ESD , 食道扁平上皮癌 , MM , SM1 pp.405-416
Published Date 2009/3/25
DOI https://doi.org/10.11477/mf.1403101610
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 158 patients who had esophageal squamous cell carcinoma(SCC)were treated by endoscopic submucosal dissection(ESD)from Jan. 2,000 to Dec. 2006. The invasion depth was divided as epithelium(EP),Lamina propria mucosa(LPM), musucularis mucosa(MM)and submuosal layer. When the depth of submucosal invasion was 200 micrometers or less, the invasion depth was defined as SM1.

 In this study, out of 158 patients 28 patients had MM SCC, and 12 patients had SM1 SCC. The additional therapies such as Esophagectomy or Chemo Radio Therapy(CRT)were recommended to the patients, when lymphatic permeation was found.

 Among the patients who had MM SCC,5 patients had lymphatic permeation. Among the patients who had SM1 SCC,4 patients had lymphatic permeation. 2 MM and 2 SM1 patients were treated by CRT and the other 5 patients who had lymphatic permeation refused the additional therapy because of other diseases. All 4 patients who were treated by CRT are alive, but lymph node metastasis was found in 2 of the patients who refused CRT. One died of esophageal SCC, and one died of another disease. No lymph node metastasis was found in 23 patients who had MM without lymphatic permeation, and 8 patients who had SM1 without lymphatic permeation. According to our data, the indication of esophageal ESD could be expanded for MM or SM1 SCC without lymphatic permeation.


Copyright © 2009, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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