国際医療福祉大学成田病院における5年間の結膜・眼瞼および眼窩腫瘍統計

A 5-year epidemiological study of ocular and orbital tumors at the International University of Health and Welfare, Narita Hospital

要約　背景と目的：国際医療福祉大学成田病院において病理組織診で確定診断した結膜・眼瞼および眼窩腫瘍症例の5年間の統計を検証した。

対象と方法：2020年3月〜2025年3月に成田病院において病理組織診で確定診断した結膜・眼瞼および眼窩腫瘍156例を対象とした。部位別の良性・悪性腫瘍の割合，悪性リンパ腫の割合について検証し，千葉大学医学部附属病院眼科の10年統計（BMC Ophthalmol, 2021）と比較検討した。

結果：対象症例の病理組織診断時の年齢は平均63.1±19.3歳，男性77名，女性79名であった。156例中，結膜・眼瞼腫瘍は134例，眼窩腫瘍は22例であった。また結膜・眼瞼腫瘍134例のうち109例は良性，25例は悪性であり，眼窩腫瘍22例のうち19例は良性，3例は悪性であった。全悪性腫瘍28例の内訳は，悪性リンパ腫12例，基底細胞癌8例，扁平上皮癌3例，脂腺癌2例，悪性黒色腫・上皮内癌・転移例が各1例であり，悪性リンパ腫が最も多かった。悪性リンパ腫と診断された12例はすべてMALTリンパ腫であった。対象症例156例中悪性リンパ腫の割合は7.7％で，千葉大学病院の10年統計の19.9％と比較して著しく低かった。

考按と結論：悪性リンパ腫の割合が既報と比較して少なかった。地域の人口構成，医療アクセス，病診連携などの要因の影響を受けている可能性がある。

Abstract　Purpose：This study aimed to evaluate a 5-year statistical analysis of conjunctival, eyelid, and orbital tumors that were histopathologically diagnosed at the International University of Health and Welfare（IUHW）, Narita Hospital.

Methods：We analyzed 156 cases of conjunctival, eyelid, and orbital tumors that were histopathologically confirmed at IUHW, Narita Hospital, between March 2020 and March 2025. The proportions of benign and malignant tumors by anatomical site and the proportion of malignant lymphomas were examined. These findings were compared with the 10-year statistics from the Department of Ophthalmology at Chiba University.

Results：The cohort consisted of 77 men and 79 women, and the mean age at the time of pathological diagnosis was 63.1±19.3 years. Of the 156 cases, 134 were conjunctival or eyelid tumors, while 22 were orbital tumors. In total, 109 of the conjunctival and eyelid tumors were benign and 25 were malignant. Among the orbital tumors, 19 were benign and three were malignant. The 28 malignant tumors included 12 malignant lymphomas, two sebaceous carcinomas, eight basal cell carcinomas, three squamous cell carcinomas, one malignant melanoma, one carcinoma in situ, and one metastatic tumor. All 12 cases of lymphoma were diagnosed as Mucosa-associated lymphoid tissue（MALT） lymphomas. The proportion of malignant lymphomas among all 156 cases was 7.7％, which was markedly lower than the 19.9％ reported in the 10-year statistics from Chiba University Hospital.

Discussion and Conclusion：The proportion of malignant lymphomas in our study was lower than that previously reported. This discrepancy may be influenced by regional demographic composition, healthcare access, and hospital-clinic collaboration systems.