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Validation of Transcranial Doppler Method to Evaluate the Effects of Mastication on Cerebral Blood Flow Kimiko Sugiyama 1 , Chiharu Okumura 2 , Shin-ichiro Watanabe 3 pp.473-482
Published Date 1999/12/15
DOI https://doi.org/10.11477/mf.1681900532

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  • Abstract
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 In this study, we tried to study the effect of mastication movement on the brain function in humans.

 For that purpose, the relation between mastication and cerebral blood flow was studied in twenty young peoples averages 26.1 y. o. applying the transcranial doppler method (TCD, Multi-DopX DWL Ltd.) to detect blood flow in the middle cerebral artery (MCA). At the same time, we checked blood pressure and pulse rates (Space Labs Inc) before and during chewing movement. The participants were given Glico Kiss Mine® Dentalcare gum to obtain mastication movement by chewing.

 In results, it was possible to detect the MCA blood flow with TCD on all twenty individuals. The reproducibility of our data was confirmed by the repeat examination on twelve out of 20 individuals. The increase in the average MCA blood flow with chewing was 12.10%, in average pulse rates was 10.29%. The average systolic and diastolic blood pressure was 4.24% and 9.63% observed respectively, when they were compared before and during mastication movement. Their T-test were P<0.001, P<0.001, P<0.005 and P<0.001 respectively.

 In conclusion, it was confirmed that using the TCD method an increment of cerebral blood flow by chewing occurred suggesting an increase in brain function by the mastication movement in young peoples as already shown by the PET scan.


Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1405 印刷版ISSN 0022-8370 医学書院

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