Secondary empty sella syndrome—自験3例と文献的考察

Secondary Empty Sella Syndrome: Report of three cases and review of the literature

I．はじめに

　empty sellaはBusch^4）らの報告に始まり，近年ではCT scan, metrizamide CT脳槽造影などの検査の普及に伴い，決して稀な疾患ではないとされている．一方，手術，放射線治療などに関連して発症したempty sellaはsecondary empty sella syndromeとして区別され^20），その報告は比較的稀^11,13）である．

　われわれは，これまで3例のsecondary empty sellasyndromeを経験したので，その成因，治療，さらには予防にも言及し，若干の文献的考察を加えて報告する．

Three cases of the secondary empty sella syndrome werereported.

Case 1. A 57-year-old female was admitted to our clinicbecause of recurrent visual disturbance. Fourteen yearspreviously a pituitary adenoma was diagnosed and twocourses of radiation therapy was given elsewhere, the totaldosage being unknown. Pneumoencephalography revealedair collection in the sellar cavity. Exploratory craniotomydemonstrated an empty sella with downward migration ofthe optic nerve and chiasm.

Case 2. A 40-year-old female was readmitted to our clinicfor possible recurrent pituitary adenoma.