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Bilateral bullous keratopathy with artificial iris: a case report Kazuyuki Majima 1 , Akiko Jinno 1,2 , Yuuichi Shirakawa 3 , Kenji Fukuzawa 3 , Motohiro Kamei 1 , Tsutomu Inatomi 3 1Department of Ophthalmology, Aichi Medical University 2Miyake Eye Hospital 3Department of Ophthalmology, Center for Sensory Organ, National Center for Geriatrics and Gerontology pp.617-621
Published Date 2022/5/15
DOI https://doi.org/10.11477/mf.1410214377

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Abstract Purpose:Various complications of artificial iris transplantation for cosmetic purposes have been reported, including iritis, corneal endothelial damage, cataracts, and secondary glaucoma. We describe a case of bilateral bullous keratopathy after insertion of an artificial iris for cosmetic purposes in India.

Case:The patient was a 46-year-old man who underwent bilateral artificial iris implantation in India in 2017. In early December 2020, he began to experience foggy vision, decreased visual acuity, and eye pain, after which he visited his previous doctor. Corrected visual acuity was 0.2 in the right eye and 0.03 in the left eye;intraocular pressure was 12 mmHg in the right eye and 13 mmHg in the left eye. Slit lamp examination revealed corneal edemas in both eyes and an artificial iris on the iris. Corneal endothelial cell density was not measurable. Anterior segment optical coherence tomography showed a corneal thickness of 698 μm in the right eye and 747 μm in the left eye, and an anterior chamber depth of 3.23 mm in the right eye and 3.17 mm in the left eye, and revealed the possibility that the artificial iris was in contact with the corneal endothelium. The artificial iris was removed and DSAEK was performed to treat the bullous keratopathy in both eyes caused by the artificial iris. Post-operative corrected visual acuity improved to 0.6 in the right eye and 0.4 in the left eye.

Conclusion:We experienced a case of bilateral bullous keratopathy caused by artificial iris transplantation for cosmetic purposes. Chronic physical tissue damage and inflammation caused by the artificial iris appear to have caused corneal endothelial cell loss. This case suggested that cosmetic artificial iris cause irreversible complications.


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