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A case of fungal scleritis after subtenon triamcinolone acetonide injection for BRVO Akito Nagae 1 , Hidetaka Masahara 1 , Hiroki Sato 1 , Kenichiro Aso 1 , Keisuke Yata 1 , Ryuya Hashimoto 1 , Takatoshi Maeno 1 1Department of Ophthalmology, Toho Uiniversity Sakura Medical Center pp.622-626
Published Date 2022/5/15
DOI https://doi.org/10.11477/mf.1410214378
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Abstract Purpose:Fungal scleritis is a rare disease that develops upon subtenon triamcinolone acetonide(STTA)injection. A case of fungal scleritis caused by Scedosporium following STTA injection for macular edema associated with branch retinal vein occlusion(BRVO)is described herein.

Case:This report describes the case of a 62-year-old man who received STTA for macular edema associated with BRVO in the left eye. The patient experienced hyperemia and pain 78 days after STTA and chemosis 84 days after STTA, leading to the rapid deterioration of visual acuity. Severe inflammation developed in the anterior chamber, and yellow lesions were found in the subconjunctival area on the inferior nasal side consistent with the injection site 90 days after STTA. An orbital MRI revealed abscess in the posterior Tenon's capsule. Scedosporium was detected during culture testing. Serous retinal detachment developed during the course of treatment with antifungal agents. Surgical debridement was difficult. Repeated posterior subtenon miconazole injections twice a week were effective. At one year after the start of treatment, the abscess and findings of serous retinal detachment disappeared, but the visual acuity decreased to hand motion.

Conclusion:Fungal scleritis was suspected because it usually occurs several months after STTA. Scedosporium might have adhered to the needle tip used in the STTA, but the direct cause was unknown. It is crucial to ensure that the needle tip is clean before performing STTA.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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