がん研究会有明病院における眼部腫瘍性疾患の臨床病理学的検討

A ten year review of ocular tumors at The Cancer Institute Hospital of JFCR

要約　目的：がん研究会有明病院での過去10年間に病理学的確定診断を得た眼部腫瘍に関する報告。

対象と方法：2005年3月〜2015年3月の間に当院で手術を行い，病理診断を得た眼部腫瘍症例715例を対象とし，病理組織学的診断別頻度についてretrospectiveに検討した。

結果：悪性は233例，良性は482例で，発生部位は眼窩195例，眼瞼338例，結膜174例，眼球内8例であった。悪性腫瘍は，眼窩と結膜では悪性リンパ腫が最多で，眼瞼は脂腺癌，基底細胞癌の順であった。眼球内腫瘍は悪性黒色腫が最多であった。

結論：眼窩，結膜の悪性腫瘍では悪性リンパ腫，眼瞼では脂腺癌が最多で，既報と比較すると悪性リンパ腫の症例が増加していた。

Abstract　Purpose: To present a ten-year review of ocular tumors diagnosed at the Department Ophthalmology, The Cancer Institute Hospital Of JFCR.

Cases and Method: This study was made on a total of 715 cases which were pathologically diagnosed as tumor of orbit, eyelid, conjunctiva and intraocular and was based on data collected from clinical records of operations performed at The Cancer Institute Hospital Of JFCR for 10 years through March 2015. Histopathological diagnoses were classified and analyzed retrospectively in term of frequency.

Findings: The series comprised 233 cases of malignant tumor and 482 cases of benign tumor. Tumors were present in the orbit 195 cases, eyelid 338 cases, conjunctiva 174 cases, and intraocular 8 cases. Among malignancy of orbit and conjunctiva, malignant lymphoma was the most frequent. Among malignancy of eyelid, sebaceous cell carcinoma was the most frequent, followed by basal cell carcinoma. Among intraocular tumors, malignant melanoma was the most frequent.

Result: The study showed that malignant lymphoma had the highest incidence rate in malignancy of orbit and conjunctiva, and sebaceous cell carcinoma had the most frequent among nalignancies of the eyelid.

Conclusion: The number of cases diagnosed as malignant lymphoma increased compared with the earlier reports.