網膜静脈分枝閉塞症の非観血的治療での視力と中心網膜厚

Visual acuity and central retinal thickness in branch retinal vein occlusion under noninvasive therapy

要約　目的：網膜静脈分枝閉塞症の2年以内の経過中での視力と中心網膜厚との関連の報告。対象と方法：新鮮な網膜静脈分枝閉塞症44例44眼を対象とした。男性18例，女性26例で，年齢は42～87歳（平均69歳）である。35眼に抗凝固薬，23眼に光凝固，5眼にベバシズマブ硝子体注射などを行った。34例で12か月，24例で24か月間，中心網膜厚などを測定した。結果：視力は6～12か月で安定した。視力と中心網膜厚値は緩やかに相関した。12か月以降の視力は，初診時視力と3か月以上の中心網膜厚値を反映した。中心窩に網膜下液があると，視力とその後の最高視力は相関しなかった。結論：黄斑浮腫がある網膜静脈分枝閉塞症で中心網膜厚の高値が6か月以降も持続する症例では，中心網膜厚値が早期に正常化した症例よりも視力転帰が不良であった。

Abstract.　Purpose：To report the correlation between visual acuity and central retinal thickness in branch retinal vein occlusion（BRVO）up to 2 years of treatment. Cases and Method：This study was made on 44 eyes of 44 cases with BRVO in its acute stage. The series comprised 18 males and 26 females. The age ranged from 42 to 87 years,average 69 years. Thirty-five eyes received systemic anticoagulant,23 eyes were treated by photocoagulation,and 5 eyes received vitreal injection of bevacizumab. Central retinal thickness was measured in 34 eyes for 12 months and in 24 eyes for 24 months. Results：Visual acuity stabilized after 6 to 12 months. Visual acuity was positively correlated with central retinal thickness. Visual acuity later than 12 months showed a close correlation with central retinal thickness after 3 months. Visual acuity failed to improve when subfoveal fluid was present. Conclusion：In BRVO with macular edema,visual outcome was poor when central retinal thickness was persistently high for over 6 months.