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Prediction of Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy:Combined Use of Heart Rate Variability and Signal Averaged Electrocardiogram Shozo Inoue 1 , Shoso Nezuo 1 , Yosuke Kawahara 1 , Junji Tanaka 1 , Keiji Tamura 1 , Yasuhiro Saito 1 , Ryouji Suetsuna 1 , Masanobu Samukawa 1 , Toshitami Sawayama 1 1Division of Cardiology, Department of Medicine, Kawasaki Medical School Keyword: 肥大型心筋症 , 心拍変動スペクトル解析 , 加算平均心電図 , hypertrophic cardiomyopathy , heart rate variavility , signal averaged electrocardio gram pp.647-650
Published Date 1996/6/15
DOI https://doi.org/10.11477/mf.1404901275

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  • Abstract
  • Look Inside

HF in Heart Rate Variability (HRV) which reduces vulnerability to ventricular arrhythmia, is revealed as adefence against ventricular tachycardia (VT). Late Potential (LP) in Signal Averaged Electrocardiogram (SAE) which means anatomic substrates of arrhyth- mias, is revealed as causative of VT. Purpose. The aim of this study is to investigate whether the combination of LP and HF is a predictor of VT in patients with hypertrophic cardiomyopathy (HCM). Methods and Results. In 65 HCM patients, HRV was analysed from 24-h ECG recordings. In 36 out of 65 patients SAE was recorded at the same time. The relations among HF, LP and VT were assessed. HF was depressed in patients with VT, but positive-LP indexes (fQRS>120, LAS40>40, RMS40<20) did not correlate with the presence of VT. Patients with severely depressed HF and positive-LP indexes, had near-miss cardiac sudden death. By contrast, in patients with severely depressed HF and normal fQRS duration, VT did not occur. Patients with mildly depressed HF and fQRS>120ms, had mild correlation with VT. But patients with nor-mal HF and fQRS>120ms did not correlate with VT. These findings suggest that depressed HF with positive-LP index easily developes VT. Conclusion. It is con-cluded that the combination of HRV and SAE seems to be useful as a predictor of VT in patients with HCM.


Copyright © 1996, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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