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以前当教室の長谷川が発表したAMIのST偏位と梗塞責任枝(IRA)との関連を前向き調査するため,1990年から5年間に入院したAMI中IRAがRCAもしくはLCXであった36例につき“長谷川lの規準”の妥当性を検討.①『aVL;ST上昇+II,III,aVF;ST下降』ならばLCX seg llor 12がIRA,②『II,III,aVF;ST上昇』ならばRCA or LCXseg 13がIRA,③『II,III,aVF;ST上昇+V1;ST上昇』ならばRCA seg1がIRAという各規準はいずれも有意な指標であった.一方,II,III,aVF;ST上昇を認めた場合,IRAがRCAかLCX seg 13かの鑑別は④『同時にV6のST上昇を伴うかIのST下降を欠けば』LCX seg 13がIRAという規準は有意でなかった.しかし,II,III,aVFのST偏位にかかわらず『V6;ST上昇』に着目すればLCXがIRAと判別できた.⑤『V3:ST下降/aVF;ST上昇比が有意に大』ならばLCX seg 13がIRAとした規準で,RCAとの判別の基準値を求めるとこの比が0.9以上ならばLCX seg 13がIRAであった.“長谷川の規準”はAMIにおけるIRAの推定に有用なことが裏づけられた.
To investigate the diagnostic criteria for infarct-related coronary arteries (IRA) by electrocardiogra-phic ST-segment deviations in the acute stage of myocardial infarction (AMI), we studied, prospec-tively, 36 patients classified by means of “Hasegawa's criteria”. There were twenty-one patients with rightcoronary artery (RCA), and 15 patients with left circumflex artery (LCX) occlusions. The following results were obtained. <criteria 1> ; when there was ST segment elevation in lead aVL associated with ST depression in leads II. III. aVF caused by LCX segment (seg)11 or seg12 occlusion, the sensitivity (Sens.) and specificity (Spcf.) were 87.5%. 92.9%, respectively. <criteria 2> ; When there was ST elevation in leads II, III, aVF caused by RCA or LCX seg13 occlusion, the Sens. and Spcf. were 92.9%, 87.5%, respectively. <criteria 3> ; When there was ST elevation in leads II, III aVF associated with V1, caused by RCA segl occlu-sion. the Sens. and Spcf. were 40.0%. 100%, respectively. <criteria 4> ; When there was differential diagnosis of RCA and LCX seg13 occlusion due to ST elevation in leads II, III, aVF, and when there was ST elevation in lead V6 and/or lack of ST depression in lead I cause by LCX seg13 occlusion, the Sens. and Spcf. were 40.0%, 81.0%, respectively. When the presence of ST elevation in lead V6 was taken into account, RCA could he differentiated from LCX seg13 occlusion. In other words, if there is ST segment elevation in lead V6, IRA is LCX. The Sens. and Spcf. were 46.7%, 90.5%, respec-tively. <criteria 5> ; When there was differential diag-nosis of RCA and LCX seg13 occlusion due to ST elevation in leads II, III, aVF, the ST depression in lead V3/ST elevation in lead aVF (V3 ; ST ↓ /aVF ; ST↑ ) ratio was significantly larger in LCX seg13. We demon-strated that the most beneficial ratio was 0.9. In other words, the V3 ; ST ↓ /aVF ; ST ↑ ratio≧0.9 means LCX seg13 occlusion. The Sens. and Spcf. were 75.0%, 88.2%, respectively. The result of this study was that these ECG criteria (“Hasegawa's criteria”) proved to be useful for diagnosis of IRA in AMI.
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