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Refractory Heart Failure due to a Late Complication after Mitral Valvuloplasty and MAZE Surgery:A case report Hirotaka Adachi 1 , Yoshinori Oda 2 , Hirohide Kondo 2 , Yoji Hirayama 1 , Hiroshi Sato 1 , Akira Yamashina 1 1The Second Department of Internal Medicine, Tokyo Medical University 2Division of Cardiology, Kosei Chuo General Hospital Keyword: MAZE術 , 遠隔期難治性心不全 , αhANP , MAZE surgery , refractory heart failure with a late complication pp.199-203
Published Date 2003/2/1
DOI https://doi.org/10.11477/mf.1404100632

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  • Abstract
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Summary

 The patient, a 65-year-old male, had been treated for severe mitral valve regurgitation accompanied by chronic atrial fibrillation. He had undergone mitral valvuloplasty and MAZE surgery for atrial fibrillation at the age of 63, because of repeated episodes of acute heart failure. Cardiac function improved transiently immediately after surgery,but it deteriorated gradually. Finally, diuretics were required one year after surgery. The patient was re-hospitalized due to acute deterioration of heart failure, and poor response to large doses of diuretics or catecholamines. However, α human natriuretic peptide (αhANP) proved very effective for diuresis. Echocardiography revealed no regurgitation in the valves including the mitral valve, and sinus rhythm was confirmed by electrophysiological studies. Pharmacological evaluation with Swann-Ganz catheter, which was performed following stabilization of the patient's condition, demonstrated the efficacy of αhANP. These findings suggested that the exhaustion of endogenous ANP may play an important role in the progression of heart failure, even in the chronic phase after MAZE surgery.


Copyright © 2003, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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