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Rectal Tumors in Ulcerative Colitis, Report of a Case Makoto Kutsukawa 1 , Kazuo Ohtsuka 1 , Haruo Ikeda 1 , Fumio Ishida 1 , Shigeharu Hamatani 2 , Shin-ei Kudo 1 1Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan 2Department of Pathology, Showa University Northern Yokohama Hospital, Yokohama, Japan Keyword: 潰瘍性大腸炎 , 大腸癌 , dysplasia , 色素内視鏡 , 拡大内視鏡 pp.1329-1340
Published Date 2013/8/25
DOI https://doi.org/10.11477/mf.1403113924

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 A 51-year-old woman was referred to our hospital for scrunity of a rectal protruded lesion which had been detected by CS(colonoscopy)for positive fecal blood test in another hospital. She was diagnosed as ulcerative colitis when she was 18 years old, but she stopped medication by herself 20 years ago. CS in our hospital revealed two other flat lesions near the rectal protruded lesion.

 Pathological findings of the biopsy specimens revealed adenocarcinoma from protruded lesion and dysplasia from flat lesions. The lesions were diagnosed as UC associated with colon cancer and dysplasia, and laparoscopically assisted ileal j-pouch-Anal Anastomosis was done. Pathological findings of the surgical specimens revealed massively invasive submucosal cancer with low to high grade dysplasia.

 Low grade dysplasias with positive p53 staining were seen out of the lesions which were diagnosed as cancer and dysplasia by CS. These couldn't be diagnosed with only HE staining.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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