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Esophageal Mucosal Bridge, Report of Six Clinical Cases and a Review of the Literature Tukafami Kogawa 1 , Hiroshi Ichikawa 1 , Toshiki Takemura 2 , Keiji Fukumoto 2 , Motoharu Kondo 2 1Internal Medicine, Maizuru Red Cross Hospital 2The First Department of Internul Medicine, Kyoto Prefecturul University of Medicine pp.423-432
Published Date 1989/4/25
DOI https://doi.org/10.11477/mf.1403106434

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  • Abstract
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 Esophageal mucosal bridge (EMB) is a rare condition. To date (1986), only 15 cases have been reported in world medical literature, 9 cases in English and 6 in Japanese.

 Six cases of EMB are presented. Twenty-one cases including 6 of the author's are reviewed. Conclusions are as follows :  1) Two cases are extremely rare ones, including EMB observed in a case of Barrett-esophageal ulcer accompanying congenital broncho-esophageal fistula. No such cases have been reported in medical literature.

 2) The etiology of EMB is not yet known. Inflammation and/or ulcer of the esophagus are seen in most cases, suggesting that the etiology of EMB is acquired(Table 1).

 3) The location of EMB is mainly the middle and lower esophagus. EMB can be single or double. Intramucosal form of EMB is the one mainly recognized. In 7 cases, EMB formed in an anteroposterior direction was seen. This form is supposedly another characteristics of EMB (Table 2).

 4) Pathological conditions seen in the esophagus with EMB are varied, these are, ulcer, moniliasis, hiatal hernia, stenosis, etc (Table 2).

 5) Histological findings of EMB are normal in congenital cases. In acquired case, esophagitis, fibrosis and granulomatous tissue are demonstrated. These varied findings are presumably due to the difference in grade of inflammation and period of examination in each case.

 6) In inflammatory bowel disease, the fusion of pseudopolyposis is thought to be the main cause of mucosal bridge formation. In the esophagus, however, communication of two ulcers in the submucosa and fusion of granulomatous tissue in an anteroposterior direction are considered to be the main mechanisms for the formation of EMB (Fig. 11) . The authors consider that the follow-up studies in 3 cases support these two theories (Figs. 1, 4 and 7)


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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