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Diagnosis and Treatment of Kimura’s Disease Satoshi Yurugi 1 , Masamitsu Kuwahara 1 , Chikako Sasaki 1 , Mika Takeuchi 1 , Masayuki Harada 1 , Shiori Adachi 2 1Department of Plastic and Reconstructive Surgery, Nara Medical University 2Department of Otolaryngology, Head and Neck Surgery, Nara Medical University pp.27-34
Published Date 2023/1/10
DOI https://doi.org/10.18916/keisei.2023010008
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 Kimura’s disease, a benign disease that predominantly affects young males in Asia, is a chronic inflammatory disease with proliferations of lymph follicles in the subcutaneous soft tissues. Painless masses can occur in soft tissues throughout the body, but the parotid gland region of the face is the most common site of occurrence. Although Kimura’s disease is relatively rare, it is easy to diagnose based on its characteristics and blood test findings. There is no established treatment for this disease. Oral steroids are often the first choice, but the disease often relapses when the steroid dosage is reduced or discontinued. Steroids, cyclosporine, surgical therapy, and irradiation are commonly used in combination for Kimura’s disease. Surgical treatment is generally indicated when the mass is localized and small, but in some cases, surgery to reduce the mass may be performed for patients who would have difficulty undergoing a total resection. Mass reduction surgery can increase the efficacy of drug therapy and should be considered as an option. Individuals with Kimura’s disease and the chief complaint of a subcutaneous tumor in the buccal region may visit a plastic surgeon for surgical purposes. Although dermatologists and otolaryngologists often play a central role in first-line drug therapy, plastic surgeons should be actively involved in the surgical treatment of refractory cases.


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電子版ISSN 印刷版ISSN 0021-5228 克誠堂出版

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