卵巣顆粒膜細胞腫の晩期再発の3例

Three cases of late recurrence of ovarian granulosa cell tumors

卵巣顆粒膜細胞腫は卵巣の性索間質細胞から発生するまれな腫瘍である^1）。『卵巣腫瘍・卵管癌・腹膜癌取扱い規約 病理編，第2版』^2）では悪性腫瘍と明記されており，晩期再発をきたすことが知られている。今回我々は，卵巣顆粒膜細胞腫の晩期再発を3例経験したので報告する。

In this report, we present three cases of late recurrence of ovarian granulosa cell tumors. The patients, who were in their 50s to 70s, were diagnosed due to abnormal liver function or abdominal symptoms. The time from initial diagnosis to recurrence ranged from 7 to 16 years, and the sites of recurrence included the liver, pelvis, abdomen, and retroperitoneum. In all three cases, except for the liver metastasis, a mass with intramassive hemorrhage was found. Recurrent masses of ovarian granulosa cell tumors can present in various forms, but intramassive hemorrhage is considered to be a common characteristic. It is important to note that ovarian granulosa cell tumors have a tendency to recur late and require long–term monitoring.