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Effects of Running Speed and Duration on a Treadmill on Bone Properties in Ovariectomized Mice Akira Minematsu 1 , Osamu Yoshimura 2 1Department of Physical Therapy, Faculty of Health Science, Kio University 2Hiroshima City Rehabilitation Center Keyword: 卵巣摘出マウス(ovariectomized mice) , 走行速度と時間(running speed and duration on a treadmill) , 骨特性(bone properties) pp.380-385
Published Date 2009/6/18
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Abstract : Effects of running speed and duration on a treadmill on bone properties were investigated in ovariectomized (OVX) mice. Sixty female ICR mice, twelve-weeks-old, were used in this study. They were divided into six groups of 10 mice each : either the SHAM, OVX, OVX+running groups (AS, AL, BS, BL), randomly. Running groups ran on the treadmill at 8 (A) or 16 (B) m/min, for 25 (S) or 50 (L) min, 5 days/week, for 10 weeks, respectively. After this, both femur and tibia bones were excised from the hind limb, and removed off surrounding tissues. Thereafter, bone mechanical strength (3 point bending test), dry bone weight and also ash content of the bones were determined. Bone mechanical strength and ash content of the femur and tibia in AL, BS, and BL mice were significantly higher than those in OVX mice. Running speed had effects on the bone mechanical strength and ash content of both bones significantly. Group BL showed the maximum values in bone properties among the running groups. This study suggested that a combination of running speed and duration could affect bone properties more significantly than the amount of exercise alone.


Copyright © 2009, The Japanese Association of Rehabilitation Medicine. All rights reserved.

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電子版ISSN 印刷版ISSN 1881-3526 日本リハビリテーション医学会

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