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High frequency oscillatory ventilation(HFOV) Masaaki SAKURAYA 1 , Nobuaki SHIME 2 1Department of Emergency and Intensive Care Medicine JA Hiroshima General Hospital 2Department of Emergency and Critical Care Medicine Graduate School of Biomedical & Health Sciences Hiroshima University pp.649-658
Published Date 2018/7/1
DOI https://doi.org/10.11477/mf.3102200543
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High-frequency oscillatory ventilation (HFOV) is a unique mode of mechanical ventilation which uses non-conventional gas exchange mechanisms to deliver ventilation at very low tidal volumes and high frequencies. The present article reviews the physiological principles, basic concepts, clinical evidence, and practical applications of HFOV in adults with ARDS. HFOV was once considered an ideal lung-protective ventilatory mode. However, several randomized control trials failed to show improved patient survival with the use of HFOV despite positive effects on lung oxygenation. Inappropriate HFOV settings, especially higher mean airway pressure or stroke volume may contribute to the incidence of adverse events in patients with ARDS. Routine monitoring to evaluate pulmonary hypertension and right ventricular function should be performed when using HFOV, especially in patients with moderate or severe ARDS who are at high risk for acute cor pulmonale. Clinical limitations of HFOV include an inability to monitor end-tidal carbon dioxide, actual stroke volume and lung sounds. At this point, the indications for HFOV may be limited to a rescue mode for lethal hypoxemia in patients with severe ARDS.


Copyright © 2018, MEDICAL SCIENCES INTERNATIONAL, LTD. All rights reserved.

基本情報

電子版ISSN 2186-7852 印刷版ISSN 1883-4833 メディカル・サイエンス・インターナショナル

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