Rinsho Kensa Volume 55, Issue 11 (October 2011)
Japanese

Antiphospholipid syndrome Tatsuya Atsumi 1 1Department of Medicine Ⅱ, Hokkaido University Graduate School of Medicine Keyword: 抗カルジオリピン抗体 , β2-グリコプロテインI , ループスアンチコアグラント pp.1193-1199
Published Date 2011/10/30
DOI https://doi.org/10.11477/mf.1542102802
  • Abstract
  • Look Inside
  • Reference

Antiphospholipid syndrome is an autoimmune disease in which recurrent vascular thrombosis and/or pregnancy morbidity is associated with persistently positive antiphospholipid antibodies (aPL). Evidence shows that the dominant antigenic targets for aPL in APS are phospholipid (PL)-binding plasma proteins such as 2glycoprotein I and prothrombin. In daily practice, aPL play a role as markers of APS. However, the determination of aPL is not easy due to their heterogeneity. It is recommended to test aPL as a combination of ELISAs and clotting assays.


Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.

基本情報

04851420.55.11.jpg
臨床検査
55巻11号 (2011年10月)
電子版ISSN 1882-1367 印刷版ISSN 0485-1420 医学書院

関連文献

もっと見る

文献を共有