Progress in personalized medicine using pharmacogenetic testing Kaname Nakatani 1 , Tsutomu Nobori 2 1Department of Order-made Medicin, Mie University Hospital 2Department of Laboratory Medicine, Mie University Graduate School of Medicine Keyword: ファーマコゲノミクス , 薬剤代謝酵素 , オーダーメイド医療 pp.1607-1613
Published Date 2010/12/15
DOI https://doi.org/10.11477/mf.1542102487
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A large amount of genetic data and drug-response genotyping techniques play an important role in movement of pharmacogenetic study into the clinical arena. A number of practical problems can simultaneously arise in the clinical application. Those are ethical problem, analytical technique, cost and clinical efficacy, and so on. The development of analytical equipment and accumulation of clinical data enable some pharmacogenetic tests to be applied in routine diagnostic tests to predict drug response. Pharmacogenetic testing should be integrated with drug therapy, so-called companion diagnosis, and provide clinically useful and personalized information to the patient and physician.

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