鼻アレルギー特異的減感作療法の遠隔成績

Long-Term Efficacy of Immunotherapy for Perennial Nasal Allergy

I．緒言

　鼻アレルギーはI型アレルギーの代表疾患の一つと考えられ，近年患者数が著明に増加していることは広く知られている。

　本疾患の治療法としては減感作療法，薬物療法，外科的療法などが挙げられるが，なかでも特異的減感作療法は本疾患に対する根本的治療法としてその中核をなしている。

　In this study, the efficacy of immunotherapy performed in our hospitals was analysed.

　According to the symptom scores obtained from 30 patients, it was recognized that the most remarkable improvements of allergic symptoms were obtained within 3 to 6 months, but no further improvements were observed after this period of treatments though the immunotherapies were continued for more than 6 months.

　To evaluate the long-term efficacy of immunotherapy, questionaires were sent to 42 patients who had previously received the immunotherapies. Approximately 70% of all patients showed persistent asymptomatic conditions for about 2 to 3 years after the final injection. There was no significant difference between the two groups that had received the long-term immunotherapy and that had discontinued immunotherapy after about 1 year of the treatment.