耳下腺腫瘍に合併した巨細胞腫2症例の経験と文献的考察

Giant Cell Tumor of the Parotid Gland Associated with Mixed Tumor: A Report of Two Cases and Review of the Literature

　I．緒言

　耳下腺腫瘍，特に悪性のものは再発し易く，その治療は困難である場合が少なくない。我々は今回耳下腺の多形腺癌および多形腺腫に骨の巨細胞腫類似の多核巨細胞浸潤を伴った2症例を経験した。甲状腺，膵臓などの多形腺癌で同様の病理所見をみた例はいくつか報告があるが，耳下腺においてはそのようた報告は，検索した範囲では見出しえず，極めて稀有のことと考えられたので，若干の文献学的考察を加えて報告した。

　Two cases of very rare mixed tumor incidentally associated with giant cell tumor which was resembling with that of bone were reported. The first case was a 48-year-old housewife with a recurrent left parotid gland tumor which had never been irradiated. The pathological diagnosis was initially reactive hyperplasia, then malignant mixed tumor, and finally carcinoma in pleomorphic adenoma and anaplastic carcinoma with many multinucleated giant cells. The second case was a 81-year-old man with an expansive right parotid gland tumor, which took a decade before sudden enlargement. The tumor was composed of pleomorphic adenoma and giant cell tumor.