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I.緒言
脳脊髄液が鼻腔から流出する状態を,鼻性髄液漏(CSF rhinorrhea)と呼び,この現象そのものは紀元2世紀のGalenの時代から知られていたが,1682年Willisによって初めて記載され,1899年Thomsonの論文以来ひとつの疾患単位としてその概念が確立され,以後多数の報告がみられるようになった。この疾患は種々の原因でおこるが(図1),大別すると,traumaticとnontraumaticに分けられる。従来の報告では,労働災害・交通事故・手術などによるtraumatic CSF rhinorrheaが圧倒的に多く,またその外科的な修復も脳外科医による開頭法に従って行われるものが多い。今回われわれは,下垂体腺腫の開頭手術,放射線照射後にCSF rhinorrheaをきたしたため,脳外科的に閉鎖術を数回施行したのちもCSF rhinorrheaの再発を認めた症例に対して,経上顎洞経由で漏部を閉鎖することに成功したので報告する。
Cerebrospinal fluid rhinorrhea (CSF rhinorrhea) is divided into traumatic and nontraumatic types. This paper reports a case of nontraumatic CSF rhinorrhea, which is relatively rare.
A 24-year-old man was operated on for removal of a pituitary adenoma (frontal craniotomy) in February, 1971, and received postoperative Liniac irradiation (5040r). Seven years after the operation the pituitary adenoma was reccured, and he underwent the same operation and postoperative iradiation. About 9 months after the second surgery, he developed CSF rhinorrhea and meningitis. Several operations for closure of fistula by neurosurgeons were unsuccessful. We performed a transmaxillay approach for its closure in December, 1980, with the successful result. The postoperative course was uneventful.
This paper discusses CSF rhinorrhea in general, and emphasizes the role of otolaryngologists, as well as neurosurgeons, in the repair of CSF rhinorrhea.
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