耳鼻咽喉科手術によるリンパ球Subpopulationの変動

THE CHANGE OF LYMPHOCYTE POPULATION AFTER SURGERY IN ENT

　I．はじめに

　われわれは悪性腫瘍患者の免疫能のparameterの一つとして，リンパ球のsubpopulationを測定し，T細胞は，悪性腫瘍患者と良性疾患患者との間に有意差のあることをすでに報告した^1）。その後，悪性腫瘍患者について治療経過とともに細胞が変動し，効果判定の指標となりうることを報告した^2）。そこで今回，手術による影響をみるために耳鼻咽喉科領域の良性疾患患者について，リンパ球のsubpopulationを測定したので報告する。

　On 31 non-cancer patients, the lymphocyte population in the peripheral blood was measured before and after surgery. The lymphocyte population was examined by E (T cell) and EAC (B cell) rosette forming test.

　The number of T cells decreased temporarily a day after operation and then increased. In the cases received surgery under local anesthesia, the number of T cells recovered in 3 to 8 days after operation and in the cases under general anesthesia they recovered in 12 to 20 days after operation.

　The cause of this temporary depression of the number of T cells was still uncertain, but it might be due to emotional stress.

　For cancer treatment, it seemed to be important that the number of T cell decreased by surgery.