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從來内耳の疾患としては,内耳奇形,内耳炎,聽神經炎,内耳細胞の退行性變化等が擧げられている。又一方内耳骨殻の疾患,内耳血管の疾患が論じられている。而して内耳を形成しているものを見るに,最外部は骨性迷路であり,次いで膜樣迷路があり,これらの間に神經と血管があり,最も内部に内耳液が滿されている。
從つて内耳に於て,疾患として擧げられていないものは内耳液のみである。それでは内耳液は病變を呈しないかというと,そうではない。内耳炎に於ては内耳液は化膿性となり,血管神經症では水腫性となると考えられている。又一方動物實驗に於ける病理組織上の所見からは,漿液性炎症とも稱すべきものを得ているのである。
GOTO proposes a new term, the diseases of endolymph, to desiganate the condition that leads to inner ear deafness. Heretofore, there were no efforts made to study the nature of the endolymphs in this disease. The present study is made on the endolymphs of rabbitswhose inner ear is normal and those which are induced into a diseased conditions and following points are noted; i.e., the cell contents, the amount of amino acid present, oxygen contents, hydrogen ion concentration, the degree in which the electrolytes are present, the sedimentation rate and other physico-chemical changes. In comparing the endolymphs under these two conditions a definite difference is noted among them which is a pathological change in that of the diseased ear. The author feels that this study has given an ample proof to the fact that the loss of hearing for higher tones in nerve deafness is due primarily to pathological changes that occur in the chara-cter of endolymph in the diseased ear. Such conditions may be divided into types which may be edematous or purulent with their respective state of being, either, acute or chronic. Furthermore, he believes that the cause of nerve deafness is due to pathological changes that may be brought about to the endolymphs and whatever other changes found in the inner ear are secondary to that change.
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