術後性鼻性化膿性腦膜炎の1治驗例—腰椎管，筋注，動注，局所，ペニシリン大量使用

　緒言

　鼻性化膿性脳膜炎は，耳性のものに較べ稀ではあるが危險なものであつて，死亡率も遙かに高く，殊に篩骨蜂窩や楔状洞のような後部副鼻腔から誘発されたものは，満足な治療を施すことがむずかしいから予後極めて不良であるとは，ペニシリン出現以前の成書に記載してある処である．又最近耳性化膿性脳膜炎のペニシリン治驗例は相次いで報告されておるが，鼻性化膿性脳膜炎はその疾患それ自体が稀なものであるからにもよるのであろうが，そのペニシリン治驗例の報告は極めて少いようである．私は最近両側副鼻腔多洞手術施行後，不幸にも併発した鼻性化膿性脳膜炎に，総量400万單位のペニシリンを使用し，幸に治癒させる事が出來たので，茲に報告する次第である．

Kawaoka experienced a complication of men-ingitis in his patient three days after bilateral pansinusectomy had been performed on the latter. In treatment, he used 4 million units of crystaline penicillin G parenterally, by intramus-cular, and intravenous routes, and intrathecal and also, locally in the area of nasal operation. After 5 days of treatment the patient was completely and successfully cured.

Reactions elicited by intrathecal use of peni-cillin, if any, were in nature of mild and transi-ent character, and in no occasion during the course of these treatments were they at all severe enough to discontinue them; intrathecal use of penicillin, as long as the spinal fluid is freely flowable through the puncture needle, is most highly effective towards allaying of men-ingitis and its inevitable state of pyrexia, the author opines.