Neurological Surgery No Shinkei Geka Volume 28, Issue 11 (November 2000)

Clinical Analysis of Hypothermia in Children with Severe Head Injury Isao TAKAHASHI 1 , Takao KITAHARA 2 , Masataka ENDO 2 , Takashi OHWADA 2 1Department of Emergency, Teine Keijinkai Hospital 2Department of Critical Care and Emergency Medicine Kitasato University Keyword: children , hypothermia , severe head injury pp.983-989
Published Date 2000/11/10
  • Abstract
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Therapeutic hypothermia may improve outcome after severe head injury, but its efficacy has not been established in children with a severe head injury. The authors evaluated the effects of hypothemia (33-34℃) in 9 severely closed head-injured children (under 16 years old). The cooling period was 3 to 21 clays (mean 9.3). Hypothermia significantly reduced ICP when it reached 33-34℃. From 3 to 6 months after injury, 6 (67%) of the 9 patients had good outcome (good recovery in 2 and moderate disability in 4), but 3 (33%) had poor outcome (severe disability in 2 and vegetative state in one). Complications, including in-fectious disorders (pneumonia, meningitis, sepsis), cardio-vascular system dysfunction (cardiac arrhythmia, hypotension), decreased platelet counts, hypokalemia, diabetes insipidus, acute pancreatitis occurred during hypothermia in 7 patients (78%). The results of this study suggest that treatment with hypothermia in chil-dren with severe head injury is often accompanied complications, but it is an effective method to control intracranial hypertension and may have improved the outcome.

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Neurological Surgery 脳神経外科
28巻11号 (2000年11月)
電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院