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Primary Pineal Embryonal Carcinoma Occurring in a Middle Aged Man Chikashi MARUKI 1 , Katsuhiko TAKARA 1 , Kazuhiro ABE 1 , Akira TSUNODA 1 , Michimasa EBATO 1 , Furitsu IKEYA 1 1Department of Neurosurgery, Koshigaya Municipal Hospital Keyword: brain tumor , pineal region , embryonal carcinoma pp.909-912
Published Date 2000/10/10
DOI https://doi.org/10.11477/mf.1436901959
  • Abstract
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A case of a primary pineal embryonal carcinoma occurring in a middle aged man is reported. A 42-year-old man suffering from headache and nausea was referred to our department. A neurological examination revealed that he had Parinaud's sign. Head CT and MRI showed a tumor in the pineal region. He was operated on using the occipital trans-tentorial approach. The tumor was partially removed and an intra-op-erative specimen was used to diagnose a kind of germ cell line tumor.

However, the tumor was diagnosed afterwards as a pure embryonal carcinoma. Three courses of PE chemotherapy followed by 30Gy of whole craniospinal irradiation and 30Gy of extended local irradiation were completed. An MRI showed the tumor to be in complete remission. Despite careful follow-up with chemotherapy every three months, a re-operation and linac radio-surgery, the tumor recurred, and dissemi-nated. The patient died due to an intra-tumoral hemorrhage. A pure primary pineal embryonal carcinoma occurring in a middle-aged person has never been reported prevoiusly in detail.


Copyright © 2000, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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