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Japanese

Intracranial Fibrous Xanthoma (Xanthofibroma) of an Infant:A case report Yoshio OHMORI 1 , Satoshi KUBO 1 , Kiyoshi YASUKOUCHI 1 , Kanji TAKEMI 1 , Masakazu IKEDA 1 , Norihiro IBAYASHI 2 1Department of Neurosurgery, Kyoto 2nd Red Cross Hospital 2Department of Neurosurgery, Kyoto Prefectural University of Medicine Keyword: Fibrous xanthoma(Xanthofibroma) , Infant , Intracranial tumor , Chest wall tumor pp.267-271
Published Date 1991/3/10
DOI https://doi.org/10.11477/mf.1436900233
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Abstract

A case of intracranial fibrous xanthoma (xanthofibro-ma) is reported. Intracranial fibrous xanthoma in infan-cy under the age of 1 year is extremely rare. This pa-tient was a 8-month-old boy with a history of convul-sive seizure. He had a previously known chest wall tumor which was diagnosed as fibrous xanthoma of the skin. Plain CT scan revealed a well defined high den-sity area in the left temporal lobe. The area was well enhanced with contrast media. At operation, it was found that the tumor did not attach to Jura mater and was almost well demarcated. Total removal of the tumor was performed. The patient has been doing well for these 6 months following craniotomy, with no sings of recurrence and no neurological deficits. Histologi-cally, the tumor was composed of fibrolastic cells and foamy phagocytic cells in storiform pattern. Some mul-tinucleated giant cells were found. Immunohistochemi-stry technique revealed that the tumor cells were nega-tive for GFAP, positive for Vimentin, positive for S-100 protein and negative for EMA. Our studies support the diagnosis of intracranial fibrous xanthoma coexistent with the same tumor found in the subcutaneous space of the chest wall of a boy under 1 year of age. We re-gard it as a rare incidence. Differential diagnosis and the characteristics of fibrous xanthoma were discussed.


Copyright © 1991, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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