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Glial Fibrillary Acidic Protein and Neurofilament Protein in Medulloblastoma Takashi TOHYAMA 1 , Osami KUBO 1 , Masako KATAHIRA 1 , Mitsuhiko SAKAIRI 1 , Taeko TAJIKA 1 , Yasuhiko TAJIKA 1 , Kohichi KITAMURA 1 1Department of Neurosurgery, Neurological Institute, Tokyo Women's Medical College Keyword: Medulloblastoma , Glial fibrillary acidic protein , Neurofilament protein , Primitive neuroectodermal tumor , Cox's proportional hazard model pp.1243-1250
Published Date 1988/10/10
DOI https://doi.org/10.11477/mf.1436202708
  • Abstract
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Medulloblastoma is the most common primitive neuroectodermal tumor (PNET) with the potential to differentiate along glial or neuronal lines. Thirty cases of medulloblastoma were immunotested by the perox-idase-antiperoxidase (PAP) method with anti-GFAP serum (DAKO) and by the avidin-biotin peroxidase complex (ABC) method with 68kd subunit of anti-NF antibody. All the cases were classified into three sub-types based on these immunohistochemical findings and were analyzed in relation to clinico-pathological fea-tures.

Fifteen of thirty medulloblastomas contained GFAP positive cells, seventeen showed cells reacting to NF.


Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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