実験的動脈瘤におけるelectric thrombosisの研究

Electric Thrombosis of the Experimental Aneurysm:Effect of Alteration in Intraaitneurysmal Hemodynamics on Thrombus Formation and Progress of Thrombosis

Ⅰ．はじめに

　近年microsurgeryの導入により脳動脈瘤のclipping,ligation或いは瘤切除が確実かつ安全に行えるようになった．しかし，その発生部位，形状の複雑さからmicrosurgical techniqueを駆使してもこれらの手術が出来ず，従来行われて来たcoating法やwrapping法によらなければならない症例も皆無ではない．このような動脈瘤に対して瘤内に人為的に血栓を作成し再出血を防ぐ方法として従来からpilojection,electricthrombosis, magnetically induced metalic thrombosis, intraluninal plastics等の方法が開発されているが，未だ一般化されていない．我々はこれ等の中から血栓作成の部位，程度を制禦しやすいelectrically induced thrombosis法をとり上げ基礎的検討を加えた．

Electric thrombosis may be one of useful method to provide protection against re-bleeding from the intracranial aneurysm which cannot be obliterated by clipping or ligation of its neck without disturbing arterial circulation. However, a better method is required to make the aneurysm to be almost completely thrombosed within one or two hours and to avoide marked damage of its wall, dislodging of the formed thrombus and excessive thrombosis.