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Changes in brain proteins in senile dementia of the Alzheimer type : Pathogenetic consideration on changes in water-soluble proteins and neurofibrillary change Shiro HARIGUHI 1 , Masatoshi TAKEDA 1 , Tsuyoshi NISHIMURA 1 1Department of Neuropsychiatry, Osaka University Medical School pp.633-640
Published Date 1985/8/10
DOI https://doi.org/10.11477/mf.1431905719
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Abstract

 The amount of total protein of the normal aged brain does not show much difference from that of the young adult, while the amount of the total brain protein in Alzheimer's disease and senile dementia of the Alzheimer type (SDAT) was lower (20%) than that of the normal aged brain. The ratios of the water-soluble protein to the total protein in the demented brains are decreased to 60~50% of those of the control brains.


Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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