小脳と随意運動—この十年の成果

The cerebellum and the voluntary movement: The progress in the last decade

I．はじめに

　訓練された運動を遂行中の無麻酔正常動物で単一ニューロン活動を記録するという方法^19）が随意運動の中枢神経機構研究の有力な手段として登場した初期の概要については十年前に本誌に総説した^43）。

　本稿ではこの方法を用いてのその後の研究成果を中心に，随意運動制御に果たす小脳の役割について考えてみる。

Abstract

　This article overviewed the advances in the last decade of our knowledge on the neural activity of the cerebellum during the voluntary limb movement.

　I. It is required for single cell studies of voluntary movement in behaving animal to solve the following two basic problems. First:the identification of target muscle or body part controlled by a neuron under the study. Second: the definition of a limb movement to be studied. The development of the methods in solving theseproblems was reviewed.