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Seizure activity and intracellular calcium Eiichi Sugaya 1 1Department of Physiology, Kanagawa Dental College pp.533-544
Published Date 1983/8/10
DOI https://doi.org/10.11477/mf.1431905515
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Summary

 In the case of seizure discharge, the mammalian cerebral cortical neuron shows a characteristic intracellular potential change, i.e. a long-lasting huge depolarization shift with a burst-like action potential on its rising phase coincident with the cortical surface seizure wave. This is called bursting activity (BA) or paroxysmal depolarization shift (PDS). The same intracellular potential change, BA, can be observed in the isolated special neurons of the Japanese land snail, Euhadra peliomphala, when pentylenetetrazole (PTZ) is applied extracellularly.


Copyright © 1983, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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