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Biosynthesis and degradation of acetylcholine receptors Saoko Atsumi 1 1Department of Anatomy, Yamanashi Medical College pp.1025-1032
Published Date 1982/12/10
DOI https://doi.org/10.11477/mf.1431905448
  • Abstract
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 Intracellular synthesis and degradation of acetylcholine receptors (AChR) of skeletal muscle fibers were described by way of morphological studies which depended on 125I-α-bungarotoxin to detect the AChR. In vivo as well as in vitro, puromycin-sensitive silver grains for AChR were observed over the Golgi complex in latissimus dorsi muscles in 11-day incubated chick embryos. The Golgi complex is presumably involved in the glycosylation and assembly of AChR molecules. Multivesicular bodies also showed heavy grains covering them, which were sensitive to puromycin treatment.


Copyright © 1982, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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