Cell kinetics of brain tumors Kazuhiro NOMURA 1 , Takao HOSHINO 1 1Brain Tumor Research Center, Department of Neurological Surgery, University of Calitbrnia. pp.30-38
Published Date 1978/2/10
DOI https://doi.org/10.11477/mf.1431904825
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 The authors review current studies on human brain tumor cell kinetics. Four growth parameters characterize the behavior of a neoplastic population: cell cycle time, growth fraction, tumor doubling time, and rate of cell loss. For prognostic purposes, tumor doubling time and cell loss play an important role, but for an understanding of the basic proliferative activity of tumor cells in relation to clinical chemotherapy, the most critical parameters are growth fraction and cell cycle time.

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