Shinkei Kenkyu no Shinpo Volume 50, Issue 2 (April 2006)

Clinical imaging of brain edema and cerebral ischemia Tatsuo Otori 1 , Yasuo Katayama 1 1Department of Internal Medicine Ⅱ, Nippon Medical School Keyword: CT , MRI , SPECT , ペナンブラ pp.233-239
Published Date 2006/4/10
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Imaging procedures such as CT(computed tomography), MRI(magnetic resonance imaging), MRA(magnetic resonance angiography), and SPECT(single photon emission computed tomography)are used in clinical settings for the diagnosis and evaluation of cerebral infarction. New diagnostic tools used very frequently include MRI diffusion imaging, MRI perfusion imaging, CT perfusion imaging, and three dimensional CT imaging. Early CT signs, MRI diffusion weighted images, MRI perfusion images, and CT perfusion images enable the diagnosis of cerebral infarction within 2 to 3 hours after the onset of its symptoms and make it possible to make proper use of a t-PA(tissue plasminogen activator). Differences encountered from time to time between diffusion weighted and perfusion weighted images(diffusion-perfusion mismatch)are considered to represent a penumbra, which is eliminated by the administration of t-PA. Brain edema occurs one day after the onset of cerebral infarction and becomes aggravated from about 5 to 7 days later. A large brain edema may cause brain hernia.

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50巻2号 (2006年4月)
電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院