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Photoreceptors for Entrainment of Circadian Rhythms Daisuke Kojima 1 , Yoshitaka Fukada 1 1Department of Biological Sciences, School of Science, The University of Tokyo Keyword: 概日リズム , 網膜神経節細胞 , 光位相同調 , メラノプシン , ipRGC , circadian rhythm , retinal ganglion cell , photoentrainment , melanopsin pp.1193-1199
Published Date 2021/11/1
DOI https://doi.org/10.11477/mf.1416201917
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Abstract

In mammals, the intrinsic circadian clock regulates various physiological rhythms, including sleep-wake cycles. These circadian rhythms can be entrained to daily 24-hour light-dark cycles by virtue of photoreception within the retina. The photo-entrainment of circadian rhythms is predominantly mediated by intrinsically photosensitive retinal ganglion cells (ipRGCs). In this article, we review the mechanisms of action of ipRGC photoreception, the retinal circuit involving ipRGCs, and the heterogeneity of ipRGCs in mice.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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