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超高齢化した本邦では,加齢による身体機能の変化が注目されており,高齢者の筋力や筋肉量の減少に対してサルコペニアという疾患概念が広く知られるようになった。末梢神経・筋疾患は二次性サルコペニアの重要な原因であり,末梢神経/筋疾患を正しく治療することは健康寿命を延ばすことにつながる。本論では,末梢神経/筋の加齢性変化を概説し,超高齢期の代表的な末梢神経/筋疾患について述べる。
Abstract
Age-related changes in physical function are attracting attention in Japan. Sarcopenia is known as the loss of skeletal muscle mass and strength in the elderly. Secondary sarcopenia due to neuromuscular disorders should be considered in patients with sarcopenia. Providing appropriate medical care for patients with neuromuscular disorders will extend healthy life expectancy. In this review, previous studies on age-related changes in the neuromuscular system were summarized and the common neuromuscular disorders in the oldest-old were reviewed.
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