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Dementia of the Oldest-Old Masaki Takao 1 1Department of Clinical Laboratory, National Center of Neurology and Psychiatry, (NCNP) National Center Hospital Keyword: 超高齢者 , 認知症 , 脳病理 , 加齢 , 多剤内服 , oldest-old , dementia , brain-pathology , aging , polypharmacy pp.1353-1359
Published Date 2020/12/1
DOI https://doi.org/10.11477/mf.1416201692
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Abstract

It is important to have a wide perspective to provide appropriate medical care for the oldest-old individuals. In terms of daily clinical practice, polypharmacy is an important factor that affects cognitive decline in older adults. The neuropathologic changes of dementia in the oldest-old individuals are associated with Alzheimer's disease, Lewy body disease, cerebrovascular disease, primary age-related tauopathy (PART), limbic-predominant age-related TDP-43 encephalopathy (LATE), and aging-related tau astrogliopathy (ARTAG).


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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