BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 70, Issue 11 (November 2018)

What is the Core Symptom and Neural Mechanism of Asperger Syndrome? From Our Ten Years of Clinical Observation of Adults with Autism Spectrum Disorder Haruhisa Ohta 1 , Kazuyo Tanji 1,2 , Ryu-ichiro Hashimoto 1,3 , Nobumasa Kato 1,4 1Medical Institute of Developmental Disabilities Research, Showa University 2Yamagata Prefectural Center for Psychiatry 3Tokyo Metropolitan University, Dept. of Human Sciences, Language Sciences 4Institute of Neuro-Psychiatry, Seiwa Hospital Keyword: 自閉スペクトラム症 , アスペルガー症候群 , 注意欠如多動症 , 脳画像 , 安静時fMRI , autism spectrum disorder , ASD , Asperger syndrome , attention-deficit hyperactivity disorder , ADHD , neuroimaging , resting-state fMRI pp.1225-1236
Published Date 2018/11/1
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In 2008, we launched a new outpatient clinic and day care service designed exclusively for adults with autism spectrum disorder (ASD). Since then, more than 6000 people visited our facility. We have also launched the Medical Institute for Developmental Disabilities Research (MIDDR) at Showa University, where neuroimaging studies with a 3.0 Tesla MRI scanner and rehabilitation studies intended to support people with ASD for job seeking were conducted for the past five years. As our subjects were found to have normal or high intelligence, we present here our research studies on Asperger syndrome patients with the focus on their resting-state functional connectivity network. We also review hypotheses of brain functioning in Asperger syndrome.

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BRAIN and NERVE-神経研究の進歩
70巻11号 (2018年11月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院